Lipomesoplasty is a technique which delivers multi-microinjections of injectable medication, symmetrically, in a specific area which is previously stablished by physical examination, ultrasound scanning and elastography. Thus, the effect will take place at the subcutaneous tissue (fat layer) level. (It must not be confused with mesotherapy)

It is an anti-inflammatory medication. It regulates blood circulation, it has lipolytic and lipoapoptotic action which activates metabolism and blood circulation in the treated area. Besides, it reduces the volume and number of adipocytes locally.

Thanks to lipomesoplasty, lipedema improves to a large extent. Loss of weight and volume is seen in the affected area, clearly improving skin texture and blood circulation.

Along with lipomesoplasty, a particular anti-inflammatory diet must be followed. In this way, weight loss through diet affects the treated areas mainly.

The clear advantage of lipomesoplasty is that is that despite not being a surgical procedure has great effects on lipedema. In addition it could be a complementary treatment of the surgical one, by significantly improving the symptoms of this disease from the first application, and producing softening of the adipose tissue, thus making the WAL surgery easier.

In order to be able to treat these pathologies, it is required to do a clinical and anthropometric assessment, ultrasound scanning and elastography.


The results which follow, are the ones achieved with average twelve-week treatments. Under specific circumstances, patients only received 6-to-9-week treatments. The treatment has very rarely been used from 18 to 24 weeks. It is not frequent to treat patients for more than 12 consecutive weeks. When more than a twelve-week treatment is required (Stage III lipedema with type II obesity or III/Morbid obesity) it is common to carry out 1-3 month weight maintenance periods with non-ketogenic diets between treatments, so that the patients change their eating habits. In this way, weight and volume loss in the lower limbs is maintained in the middle and long term.

Undoubtedly, when treating patients who suffer from both Stage III/IV lipedema and morbid obesity (which is very common), the length of treatment must be longer than the average 12-week period.

At first sight, some of the patients which follow (especially Stage I and Type I lipedema) might not seem to be suffering from lipedema before treatment. However, their medical history, laboratory tests, palpation, ultrasound scanning and elastography confirmed they had the condition. As these tests are always carried out as part of our protocol, we were able to diagnose the patients with lipedema and treat them, despite not having the slightest suspicion of the disease at first sight.

None of the photos below has been digitally retouched.

During the diagnostic visit, a comprehensive and specific blood test will be performed to diagnose lipedema and other metabolic / inflammatory diseases that frequently accompany lipedema.

It is not common to treat patients for more than 12 consecutive weeks. If a longer treatment is required we are in favour of carrying out a 2-4 month maintenance period before restarting the treatment.

Once the treatment has begun, it is vital to go to the doctor’s surgery on a weekly basis throughout the treatment. From the 4th week of treatment it might be possible to miss some of the weekly follow-up appointments.

After the treatment, monthly follow-up appointments will prevent the rebound effect from happening. During this maintenance period, patients will not be on a ketogenic diet as it might have important adverse effects if it is followed in the long term, especially without being under medical control.

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